Endocrine Abstracts

Introduction: Charcot foot is a painless progressive osteoarthropathy of one or more joints due to an underlying neurological lesion, leading to deformities of the foot by the non-infectious destruction of bones and joints.The interest of this observation is to show on the one hand the role that the education of diabetics plays in the early diagnosis of Charcot foot and on the other hand the need for a multidisciplinary team in the care of the foot of Ch...

Introduction: Growth retardation in sickle cell children is common and multifactorial. Recent evidence suggests damage to the somatotropic axis. We report the case of a patient followed for homozygous sickle cell anemia and in whom we discover an associated GH deficiency.Observation: It is a 13 year old child followed for homozygous sickle cell anemia, splenectomized for 2 years, not polytransfused. We were sent to the hematology department before a dela...

Background: Pituitary gland metastasis is rarely the initial presentation of metastatic cancer. Most cases of pituitary gland metastasis are asymptomatic with diabetes insipidus being the most common symptomatic presentation. It can rarely present with symptoms of hormone underproduction such as anterior pituitary deficiency. Although pituitary gland metastasis is rare, it is underestimated, as it is commonly misdiagnosed with pituitary gland adenoma due to the lack of clear r...

Introduction: COVID-19 is a novel pandemic affecting globally. It has led to an unprecedented global health crisis assessing health system’s preparedness to deal with health disasters. The aim of our study was to evaluate the impact of COVID-19 on the follow up care of diabetic patients.Methods: We conducted a retrospective study in 100 insulin-requiring diabetic patients. Data regarding treatment availability, weigh, glycemic control and follow up ...

Introduction: In Tunisia, the prescription of insulin analogs is increasingly « automatic » by practicians, convinced by this treatment superiority over human insulin in diabetes management. The aim of our study is to determine whether the analogs prescription modalities and advantages are known by the patients, and to assess the factors associated with this knowledge.Patient and Methods: We conducted a retrospective study including 65 diabetic...

Introduction: Neurofibromatosis type 2 (NF2) is an autosomal dominant genetic disorder that cause a growth of noncancerous tumors in the nervous system, it associates cranial schwannomas, meningiomas, and skin and ophthalmologic lesions. It is a rare condition and its association with an intrasellar arachnoidocele has not been reported yet. We report the case of a patient who presents a NF2 associated with hypopituitarism related to an intrasellar arachnoidocele.<p class="...

Introduction: Most brand-name drugs do not differ that much from their generic counterparts, so switching between the two is not an issue. Levothyroxine, however, is an exception. The question of generic equivalency of levothyroxine products has remained unanswered for several decades. The purpose of the present study was to learn whether there is a difference of dosage between brand-name and generic levothyroxine in patient with well controlled primary hypothyroidism<p cl...

Introduction: Treatment of primary hypothyroidism relies on a daily intake of levothyroxine, which dosage is determined first by the weight then by TSH levels monitoring. The daily dosage can vary with the cause of the hypothyroidism and the weight. The aim of our study was to determine if the adherence was a factor influencing the dosage of levothyroxine in a group of well-controlled hypothyroid patients.Method: We performed a cross-sectional study incl...

Introduction: Polycystic ovary syndrome (PCOS) is a common endocrine disease in women of childbearing age. This condition combines, according to the diagnostic criteria of the Rotterdam consensus 2003, clinical and/or biochemical signs of hyperandrogenism, oligo- and/or anovulation and polycystic ovaries detected by ultrasound. Thyroid diseases are also frequent in the general population. The aim of our study was to determine the prevalence of thyroid ultrasound alterations in...

Introduction: Darier disease, also known as dyskeratosis follicularis, is a rare autosomal dominant genodermatosis characterized by a persistent eruption of keratotic papules. It is caused by mutations in the ATP2A2 gene encoding sarcoendoplasmic reticulum Ca 2+ -ATPase isoform 2 in the endoplasmic reticulum. Since it is expressed in most tissues, other organs besides the skin may be involved in Darier disease. In this case, we report a patient treated for Darier disease who w...